HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.
Yumiko Nakajima, Speaker at Catalysis Conferences
National Institute of Advanced Industrial Science and Technology, Japan
Title : A well-defined Fe catalyst system bearing a tetradentate pnnp ligand: Selective synthesis of hydrosiloxanes via dehydronegative coupling of silanols with hydrosilanes


Iron complexes with low toxicity and high terrestrial abundance have recently drawn increasing attention as a new class of catalyst precursors in an attempt to develop environmentally benign and sustainable methods for organic synthesis. Intensive studies on Fe complexes have been conducted to date; however, examples of well-defined reactions remain scarce compared with those of 4d or 5d metal complexes. In this study, a well-defined iron complex system was established using PNNP-R (R = Ph and Cy) as a strong σ-donating ligand with a rigid meridional tetradentate structure. Reactive Fe(0) complexes [{Fe(PNNP-R)}2(μ-N2 )] were synthesized by the reaction of the corresponding iron diharide with NaBEt3 H and structurally fully characterized. The reaction proceeded via the iron dihydride intermediate [Fe(H)2 (PNNP-R)], which underwent H2 reductive elimination, supporting the hemilabile behavior of PNNP-R. [{Fe(PNNP-R)}2 (μ-N2 )] catalyzed dehydrogenative coupling of silanols with silanes to selectively form various hydrosiloxanes, which are important building blocks for the synthesis of a range of siloxane compounds. The system exhibited the highest catalytic efficiency among the previously reported transition-metal-catalyzed systems.

Audience Take Away:

  • One method to precisely design of Fe complexes using a strong ?-donating ligand.
  • Synthetic procedures of reactive Fe(0) complexes bearing labile N2 or silane ligands.
  • Importance of hydosiloxanes as a raw materials for the silicone production.


She received her Ph.D. from Tokyo Institute of Technology in 2005. She then worked as a Posdoc (sponsored by a Humboldt Research Fellowship) at RWTH Aachen University (2005-2007) and at RIKEN (2007-2008). She joined Kyoto University as an Assistant Professor in 2008. She spent the year 2009-2013 as a JST PRESTO project researcher. She moved National Institute of Advanced Industrial Science and Technology (AIST) as a senior researcher in 2013 and then become a team leader. Her research interests are in organometallic chemistry and coordination chemistry.