Abstract:
The development of sustainable processes for chemical synthesis, energy and petrochemical technologies is one of the major challenges and noteworthy task for 21sr century. Notably, catalysis is a key technology for achieving more sustainable processes in the chemical, pharmaceutical and material industries. Currently, more than 80% of all chemical products are made via catalysis. In this regard, the development of more selective, cost-effective and durable catalysts constitutes a key factor for the production of all kinds of chemicals today and in the future.
Novel unsaturated C10 diesters are produced via alkoxycarbonylation of ?-lactone 1 (3- ethylidene-6-vinyltetrahydro2H-pyran-2-one), derived from the telomerization of CO2 and butadiene. Key for the selective valorization of 1 is the use of a catalytic system based on PdCl2 , a chelating phosphine bearing electron-withdrawing groups and an acidic promoter. The unsaturated C10 methyl diester can be easily hydrogenated on Pd/C under mild conditions to afford its corresponding saturated diester. Subsequent hydrogenation using the homogeneous [Ru(acac)3]/Triphos catalysts gives 2- ethyloctane-1,8-diol in high yield. The overall procedure allows synthesizing new building blocks for the manufacturing of renewable polymers and polymers processing materials.
Biography:
Dr. M. Sharif is currently a Research scientist at Leibniz Institute for Catalysis, Rostock Germany. During his doctoral & postdoctoral research, Dr. Sharif has been heavily involved in synthetic organic chemistry using either classical organic chemistry methodologies or transition metal-catalyzed synthesis of a range of synthetically important organic building blocks for diverse application. Dr. Sharif is also interested in the development of novel efficient synthetic organic methodologies which allow for a “greener” synthesis of fine chemicals for potential use in material, biological and pharmaceutical applications. He has published one patent and 28 research papers in reputed reviewed journals including Chem. Commun., Green Chem., Molecular Therapy and others. He is very well familiar with modern tools of organic chemistry, catalysis and spectroscopy. He held various research positions within academics and has closely worked in industrial driven projects throughout his career with major emphasis on organic synthesis, synthetic methodology development and catalysis for target oriented organic syntheses. His research-experience and expertise cover a wide range of topics in synthetic organic chemistry, green chemistry and homogeneous catalysis. Dr. Sharif is also initiated several collaborations between leibniz Institute for Catalysis, Rostock, Germany and other research institutes/Universities in developing countries. Sharif is also an external committee member for evaluation of PhD dissertations at Jacob University Bremen, Germany. Currently, He is also working as a team leader at leibniz Institute for Catalysis, Rostock, Germany. Sharif is involved in several cooperation projects in Gulf.
