A one pot approach to catalyze suzuki-miyaura coupling reaction using (2-benzoylpyridinethiosemicarbazone)palladium(II)

Title : A one pot approach to catalyze suzuki-miyaura coupling reaction using (2-benzoylpyridinethiosemicarbazone)palladium(II)

Abstract:

Recently, our group has reported a square planar coordination compound of palladium(II) with 2-benzoylpyridine thiosemicarbazone, having chemical composition, [Pd((C6H5)(py-N1)C2=N2-N3H-C1(=S)- N4H2)Cl] { Pd(II) catalyst }. The catalytic properties of it were investigated using the Suzuki-Miyaura coupling reaction as a model. Interestingly, the Pd(II) catalyst has effectively catalyzed the cross coupling reaction between aryl halides (ArCl, ArBr or ArI) and phenyl boronic acid in EtOH/H2O mixture in basic medium at relatively low temperature (50 oC). Multiple additions of reactants in the phased manner to the same reaction vessel effectively catalyzed the reaction of ArBr with PhB(OH)2. Aryl iodide behaved similarly; aryl chloride needed more hard conditions. This catalytic activity was performed under normal atmospheric conditions in the absence of any free ligand or any promoting additive.

Audience Takeaway Notes: 

• Exploration of a novel single pot catalyst for Suzuki-Miyaura coupling reactions. 
• Easy synthesis of catalyst.
• Suzuki-Miyaura coupling reactions take place at 50 oC temperature under normal atmospheric conditions in the absence of any free ligand or any promoting additive.

Biography:

Dr. Ritu Bala studied Chemistry at Punjab University Chandigarh, India and post graduated as MSc Chemistry (Honrs. School) in year 2021. She then joined the research group of Prof. Raj Pal Sharma atthe Department of Chemistry, Punjab University, Chandigarh, India in Inorganic Chemistry. She received her PhD degree in 2007 at the same institution. Immediately after her PhD she joined BILT, India as Research scientist. And in year 2010 she joined as Assistant Professor at Department of Chemistry, Guru Nanak Dev University Amritsar. She is working on Coordination Chemistry and supervised 3 PhD scholars. At present she is working as Associate Professor in the same university and guiding three PhD research students. She has published more than 80 research articles in SCI(E) journals.