C-C bond formation

Over the past 10 years, there has been rapid advancement in the production of C-C bonds by carbometallation, particularly in reactions that are promoted by group 8–11 metals. It is now possible to securely design inter- and intramolecular processes, as well as sequences that combine the two, to produce useful substrates like carbo- and heterocycles. It was discovered that when imidazole was deprotonated with potassium t-butoxide in liquid ammonia via electrochemically induced SRN1, direct C-C bond formation at the 2-position of imidazole and benzimidazole occurred. Over the past 10 years, there has been rapid advancement in the production of C-C bonds by carbometallation, particularly in reactions that are promoted by group 8–11 metals. It is now possible to securely design inter- and intramolecular processes, as well as sequences that combine the two, to produce useful substrates like carbo- and heterocycles.

Committee Members
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Stanislaw Dzwigaj

Stanislaw Dzwigaj

Sorbonne University, France
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Anne M Gaffney

Anne M Gaffney

University of South Carolina, United States
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Victor Cerda

Victor Cerda

University of the Balearic Island, Spain
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Marta I Litter

Marta I Litter

Sapienza University of Rome, Italy
CCT 2026 Speakers
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Dae Dong Sung

Dae Dong Sung

Korea University Sejong Campus, Korea, Republic of
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Enrico Paris

Enrico Paris

CREA-IT & DIAEE, Italy
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Collin G Joseph

Collin G Joseph

University Malaysia Sabah, Malaysia
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Nina Patel

Nina Patel

University of Bath, United Kingdom

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