Over the past 10 years, there has been rapid advancement in the production of C-C bonds by carbometallation, particularly in reactions that are promoted by group 8–11 metals. It is now possible to securely design inter- and intramolecular processes, as well as sequences that combine the two, to produce useful substrates like carbo- and heterocycles. It was discovered that when imidazole was deprotonated with potassium t-butoxide in liquid ammonia via electrochemically induced SRN1, direct C-C bond formation at the 2-position of imidazole and benzimidazole occurred. Over the past 10 years, there has been rapid advancement in the production of C-C bonds by carbometallation, particularly in reactions that are promoted by group 8–11 metals. It is now possible to securely design inter- and intramolecular processes, as well as sequences that combine the two, to produce useful substrates like carbo- and heterocycles.
Stanislaw Dzwigaj
Sorbonne University, France
Dai Yeun Jeong
Jeju National University, Korea, Republic of
Marta I Litter
Sapienza University of Rome, Italy
Sergey Suchkov
R&D Director of the National Center for Human Photosynthesis, MexicoSubmit your abstract Today
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Dai Yeun Jeong, Jeju National University, Korea, Republic of
Title : The multidimensional topological shift of the KRASG12D proteins in catalytic environments and pertinent drugs-targetting
Orchidea Maria Lecian, Sapienza University of Rome, Italy