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Carboxylation

A substrate is subjected to carboxylation, a chemical process that results in the production of a carboxylic acid. Decarboxylation is the reaction in the other direction. When referring to the reaction of carbanionic reagents with CO2, the word "carbonation" in chemistry is occasionally interchanged with "carboxylation." Generally speaking, carbonation refers to the process of producing carbonates. A common reaction in organic chemistry is carboxylation. Organic halides are often converted into carboxylic acids by carbonation, namely using Grignard reagents and organolithium compounds. In the Kolbe-Schmitt reaction, sodium phenolate (the sodium salt of phenol) is treated with carbon dioxide at high pressure (100 atm) and high temperature (390 K) to produce sodium salicylate, a precursor to aspirin. causing the resultant salicylate salt to become acidic and give salicylic acid.

Committee Members
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Stanislaw Dzwigaj

Stanislaw Dzwigaj

Sorbonne University, France
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Anne M Gaffney

Anne M Gaffney

University of South Carolina, United States
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Marta I Litter

Marta I Litter

Sapienza University of Rome, Italy
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Dai Yeun Jeong

Dai Yeun Jeong

Jeju National University, Korea, Republic of
CCT 2026 Speakers
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Sergey Suchkov

Sergey Suchkov

R&D Director of the National Center for Human Photosynthesis, Mexico
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Vladislav Sadykov

Vladislav Sadykov

Novosibirsk State University, Russian Federation
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Enrico Paris

Enrico Paris

CREA-IT & DIAEE, Italy
Speaker at Catalysis, Chemical Engineering and Technology 2026 - Eleana Kordouli

Eleana Kordouli

University of Patras, Greece

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