Metal ions are necessary for the maximum activity of several enzymes. An enzyme is referred to be a metalloenzyme if it has a very strong metal binding or needs the metal ion to maintain its stable, natural form. Metal activated enzymes are those that bind metal ions less strongly, sometimes just during the catalytic cycle. Metals can function as electrophilic catalysts in metalloenzymes and metal-activated enzymes, stabilising the increased electron density or negative charge that might arise during reactions. One of the enzymes involved in this. Catalyst activity, catalyst stability, and the requirement to reduce operational and capital expenses all have an impact on the choice of the ideal reactor intake and outlet temperatures. Engineering specifications have an impact on the ultimate choice regarding design inlet temperature.