By adjusting the concentrations of ligands—non-scaffold molecules that bind to particular sites on scaffolds—phase transitions of scaffolds can be controlled. The valence of ligands, whether or not they bind directly to stickers or spacers, and the relative affinities of ligand-scaffold versus scaffold-scaffold interactions determine the modulatory effects of ligands. The concentration of scaffolds in condensates is typically diluted by all ligands. Multivalent ligands can stabilise condensates by binding directly to spacers or destabilise condensates by binding directly to stickers, in contrast to monovalent ligands, which destabilise condensates. Even when they have no effect on condensate stability, bipartite ligands that bind to stickers and spacers can change the structural arrangement of scaffold molecules there.
Stanislaw Dzwigaj
Sorbonne University, France
Dai Yeun Jeong
Asia Climate Change Education Center , Korea, Republic of
Samy Ponnusamy
MilliporeSigma, United States
Gustaaf Schoukens
Ghent University, Belgium
Oluwaseun Akinrinde
University of South Florida, United States
Maria Parfenova
Institute of Physical Materials Science, Russian Federation
Valyaev Alexander
Nuclear Safety Institute of the Russian Academy of Sciences, Russian Federation
Title : Application of vanadium and tantalum single-site zeolite catalysts in heterogeneous catalysis
Stanislaw Dzwigaj, Sorbonne University, France
Title : Indicators for evaluating green management practice of enterprises
Dai Yeun Jeong, Asia Climate Change Education Center , Korea, Republic of
Title : DOZN™3.0 - A quantitative green chemistry evaluator for a sustainable future
Samy Ponnusamy, MilliporeSigma, United States
Title : Towards integrated biodesign-inspired translational platforms to co-develop innovative biotechnologies, biomanufacturing and biomarketing to revolutionize the future of personalized & precision healthcare and life science bioindustry
Sergey Victorovich Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Nanocomposite materials for structured catalysts of fuels reforming, catalytic layers in membrane reactors for oxygen and hydrogen separation and fuel cell anodes operating in the internal reforming mode
Vladislav Sadykov, Boreskov Institute of Catalysis, Russia, Russian Federation
Title : Green nanobiocatalysts for sustainable ester production: Advancing lipase immobilization and process optimization
Praveen Dahiya, Amity University Uttar Pradesh, India