Solvents and Solvation The study of ‘host' molecules that can accommodate ‘guests' (usually other molecules or atomic ions) within their cavities has long been a foundation for what is now known as supramolecular chemistry. Since its inception, macrocycles have been a mainstay of supramolecular chemistry.
Supramolecular chemistry is a branch of chemistry that studies systems made up of a number of distinct molecular subunits or components that are held together by noncovalent forces such hydrogen bonding, electrostatic and hydrophobic interactions, halogen bonds and π- interactions. Self-assembly processes, a fundamental concern in actinide-related supramolecular chemistry, are addressed in supramolecular chemistry.