A ring of twelve or more atoms or more is commonly seen in macrocycles, which are also known as molecules and ions. Traditional examples include cyclodextrins, porphyrins, calixarenes, and crown ethers. A vast, developed area of chemistry is described by macrocycles. Macrocyclization is the process of forming macrocycles through ring-closure. For investigations on terpenoid macrocycles, groundbreaking work was reported. Ring-closing reactions' inability to promote the formation of big rings is the main obstacle to macrocyclization. Instead, tiny rings or polymers usually develop. Utilizing high-dilution reactions, which favour intramolecular processes over polymerizations in comparison to each other, can solve this kinetic issue. The many macrocyclic antibiotics known as macrolides, such as clarithromycin, have an important application. Numerous metallocofactors are bonded to porphyrins, corrins, and chlorins among other macrocyclic ligands.
Ephraim Suhir
Portland State University, United States
Thomas J J Muller
Heinrich-Heine-Universitat Dusseldorf, Germany
Stanislaw Dzwigaj
Sorbonne University, France
Dai Yeun Jeong
Jeju National University, Korea, Republic of
Ephraim Suhir
Portland State University, United States
Marta I Litter
University of General San Martin, Argentina
Abdeltif Amrane
Institute of Chemical Sciences of Rennes, France
Mikhail Kashchenko
Ural'skiy Gosudarstvennyy Lesotekhnicheskiy Universitet, Russian FederationSubmit your abstract Today
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