In order to increase the efficiency of a chemical reaction, one-pot synthesis involves putting a reactant through multiple chemical reactions in a single reactor. Chemists are very interested in this because it can reduce the need for time-consuming separation procedures and chemical compound purification while also boosting chemical yield. Tropinone's total synthesis or the Gassman indole synthesis are two examples of one-pot synthesises. Sequential one-pot syntheses can be used to produce even complex targets with multiple stereocenters, like oseltamivir, potentially reducing the overall number of steps and having significant commercial implications. Also known as a telescoping synthesis, a sequential one-pot synthesis involves adding reagents to a reactor one at a time without work-up.
Ephraim Suhir
Portland State University, United States
Thomas J J Muller
Heinrich-Heine-Universitat Dusseldorf, Germany
Stanislaw Dzwigaj
Sorbonne University, France
Dai Yeun Jeong
Jeju National University, Korea, Republic of
Haibo Ge
Texas Tech University, United States
Marta I Litter
University of General San Martin, Argentina
Luigi Antonio Pezone
Santa Maria Capua Vetere, Italy
Davide Frumento
RomaTre University, ItalySubmit your abstract Today
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