In order to increase the efficiency of a chemical reaction, one-pot synthesis involves putting a reactant through multiple chemical reactions in a single reactor. Chemists are very interested in this because it can reduce the need for time-consuming separation procedures and chemical compound purification while also boosting chemical yield. Tropinone's total synthesis or the Gassman indole synthesis are two examples of one-pot synthesises. Sequential one-pot syntheses can be used to produce even complex targets with multiple stereocenters, like oseltamivir, potentially reducing the overall number of steps and having significant commercial implications. Also known as a telescoping synthesis, a sequential one-pot synthesis involves adding reagents to a reactor one at a time without work-up.
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Sorbonne University, France
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Ghent University, Belgium
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Nuclear Safety Institute of the Russian Academy of Sciences, Russian Federation
Vladimir G Chigrinov
Hong Kong University of Science and Technology, Hong Kong
Sujit Kumar Bandyopadhyay
Variable Energy Cyclotron Centre, India
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